In order to improve the comprehensive benefit of Qilian mountain architecture system, we need to carry out a sound environmental protection design of Qilian mountain architecture, so as to adjust the scientific environmental protection coordination of every link in Qilian mountain architecture. With the acceleration of urbanization in China, the environmental protection design of buildings is also put forward higher requirements. Under the background of coordinated development, many factors affecting the environmental protection of buildings are analyzed in various aspects and angles, and reasonable solutions are given according to these problems, thus laying a certain foundation for the future development of architecture in China. this paper focuses on the implementation of the Qilian mountains ecological protection and its comprehensive management project, hoping to bring some help to the development of the Qilian mountains ecological protection.